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Ambien (zolpidem) is a prescription sedative-hypnotic medication used for short-term treatment of insomnia. It works by enhancing the effects of GABA, a neurotransmitter that slows brain activity, helping users fall asleep quickly. Ambien is available in immediate-release and extended-release (Ambien CR) formulations. The immediate-release version helps induce sleep, while the extended-release form aids in both sleep onset and maintenance.